abstract：BACKGROUND:Higher age is associated with reduced physical capability in the general population. The role of age and gender for physical performance in older adults who exercises regularly is, however, not clear, and there is also a lack of recommendations for outcomes to address physical performance for this population...

journal_title：Aging clinical and experimental research

authors： Tangen GG,Robinson HS

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Postoperative cognitive dysfunction (POCD) is a common complication after orthopedic surgery, which is not conducive to the prognosis of the elderly. AIMS:We performed this study to investigate the effects of oxycodone applied for patient-controlled intravenous analgesia (PCIA) on postoperative cognitive fu...

journal_title：Aging clinical and experimental research

authors： Gan J,Tu Q,Miao S,Lei T,Cui X,Yan J,Zhang J

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Asymmetric vestibular function, decreased plantar sensation, postural control and functional ability have been associated with fall-related wrist fractures. OBJECTIVE:To investigate whether multi-sensory training (MST) improves postural control, vestibular function, foot sensation and functional ability amo...

journal_title：Aging clinical and experimental research

authors： Baldursdottir B,Whitney SL,Ramel A,Jonsson PV,Mogensen B,Petersen H,Kristinsdottir EK

更新日期：2020-01-01 00:00:00

abstract：:Sarcopenic obesity (SO) refers to an obesity disease accompanied by low skeletal muscle quality, strength and/or function, which is more common in the elderly and seriously affects their quality of life and can lead to falls, unstable walking, balance disorders and fractures in the elderly. The increase in aging popul...

journal_title：Aging clinical and experimental research

authors： Xie WQ,Xiao GL,Fan YB,He M,Lv S,Li YS

更新日期：2019-12-16 00:00:00

abstract：OBJECTIVE:To determine the association between the level of nutritional risk and the mortality of hospitalized patients with atrial fibrillation. METHODS:In a prospective cohort study, we included patients hospitalized with atrial fibrillation in an internal medicine department in 2007. We calculated the nutritional r...

journal_title：Aging clinical and experimental research

authors： Díez-Manglano J,Clemente-Sarasa C

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Polypharmacy has been associated with worse cognitive performance, but its impact on mild cognitive impairment (MCI) progression to dementia has not been explored. AIMS:The aims of the study were to investigate the association between multidrug regimens and MCI progression, and the possible mediation of dru...

journal_title：Aging clinical and experimental research

authors： Trevisan C,Limongi F,Siviero P,Noale M,Cignarella A,Manzato E,Sergi G,Maggi S

更新日期：2019-11-22 00:00:00

abstract：:New onset epilepsy and seizures are common neurological disorders in aged people, second only to stroke and dementia. They are frequently related to other pathological conditions including stroke, trauma, tumors and neurological diseases whereas in about one-third of cases the origin is unknown. Besides the origin, th...

journal_title：Aging clinical and experimental research

authors： Losi G,Gomez-Gonzalo M,Zonta M,Chiavegato A,Carmignoto G

更新日期：2019-11-15 00:00:00

abstract：BACKGROUND AND AIM:Sarcopenia and sarcopenic obesity (SO) are associated with adverse health outcomes in older people. Data on sarcopenia- and SO-related mortality are insufficient for hospitalized older people. The aim of this study was to evaluate the relationship between sarcopenia, SO and mortality among hospitaliz...

journal_title：Aging clinical and experimental research

authors： Atmis V,Yalcin A,Silay K,Ulutas S,Bahsi R,Turgut T,Mut Sürmeli D,Selvi Öztorun H,Yaman S,Çoşarderelioğlu Ç,Aras S,Varli M

更新日期：2019-11-01 00:00:00

abstract：:Frailty has been indicated as a way for capturing biological aging of the individual and Frailty Index (FI) may serve for this purpose. This study designed the FI in a cohort of centenarians, their offspring and control subjects sex- and age-matched with offspring. The FI mean value was 0.47 (SD 0.13) in centenarians,...

journal_title：Aging clinical and experimental research

authors： Arosio B,Ferri E,Casati M,Mari D,Vitale G,Cesari M

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Multiple chronic conditions affect people's health-related quality of life (QoL) and the distributions of the conditions may differ between genders. Our goal was to examine gender differences in chronic conditions and QoL among community-living elderly in Taiwan and to examine whether differences in QoL betw...

journal_title：Aging clinical and experimental research

authors： Yu T,Enkh-Amgalan N,Zorigt G,Hsu YJ,Chen HJ,Yang HY

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Aging, cancer and its treatment all contribute to increase the risk of deconditioning and sedentary behaviors. Mixed exercise is recognized to counteract the effects of aging and deconditioning as well as improving physical capacity during cancer treatment in adults. AIMS:To determine the impact of a mixed ...

journal_title：Aging clinical and experimental research

authors： Maréchal R,Fontvieille A,Parent-Roberge H,Fülöp T,Riesco E,Pavic M,Dionne IJ

更新日期：2019-11-01 00:00:00

abstract：:Neuroinflammation and cholinergic dysfunction, leading to cognitive impairment, are hallmarks of aging and neurodegenerative disorders, including Alzheimer's disease (AD). Acetylcholinesterase inhibitors (AChEI), the symptomatic therapy in AD, attenuate and delay the cognitive deficit by enhancing cholinergic synapses...

journal_title：Aging clinical and experimental research

authors： Benfante R,Di Lascio S,Cardani S,Fornasari D

更新日期：2019-10-03 00:00:00

abstract：BACKGROUND:Fragility fracture significantly increases risk of future fracture. The fragility fracture cycle should be disrupted. The secondary fracture prevention is important for the patients with fragility hip fracture. The pharmacotherapy for osteoporosis is important for prevention of new fracture. However, many pa...

journal_title：Aging clinical and experimental research

authors： Wang P,Li Y,Zhuang H,Yu H,Cai S,Xu H,Chen Z,Lin J,Yao X

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Physical exercise and nutrition seem to have a key role in the management of hip fracture patients. AIM:To evaluate the impact of a 2-month rehabilitative protocol combined with dietetic counseling, with or without essential amino acid supplementation, on functioning in hip fracture patients. METHODS:In th...

journal_title：Aging clinical and experimental research

authors： Invernizzi M,de Sire A,D'Andrea F,Carrera D,Renò F,Migliaccio S,Iolascon G,Cisari C

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND AIMS:The Charlson Comorbidity Index (CCI) is the most widely used assessment tool to report the presence of comorbid conditions. The Barthel index (BI) is used to measure performance in activities of daily living. We prospectively investigated the performance of CCI or BI to predict length of hospital st...

journal_title：Aging clinical and experimental research

authors： Bahrmann A,Benner L,Christ M,Bertsch T,Sieber CC,Katus H,Bahrmann P

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Sepsis is more common in the elderly. TNF⍺ is recognized as an important mediator in sepsis and Toll-like receptors (TLRs) play an important role in initiating signaling cascades to produce TNF⍺. Little is known about how innate immunity is altered in healthy human aging that predisposes to sepsis. AIMS AND...

journal_title：Aging clinical and experimental research

authors： Bailey KL,Smith LM,Heires AJ,Katafiasz DM,Romberger DJ,LeVan TD

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:A lack of understanding of the causes of attrition in longitudinal studies of older adults may lead to higher attrition rates and bias longitudinal study results. In longitudinal epidemiological studies of Alzheimer's disease and related dementias, high rates of attrition may cause a systematic underestimatio...

journal_title：Aging clinical and experimental research

authors： Burke SL,Hu T,Naseh M,Fava NM,O'Driscoll J,Alvarez D,Cottler LB,Duara R

更新日期：2019-09-01 00:00:00

abstract：INTRODUCTION:Syphilis is a systemic human disease which is caused by infection with the spirochete Treponema pallidum. It is spread worldwide, and there has recently been an increase in its incidence. Neurosyphilis (NS) can have a variety of presentations; meningovascular NS is a specific affection of the Treponema whi...

journal_title：Aging clinical and experimental research

authors： Pintado Maury I,Alves M,Fonseca T

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Previous research indicates that dance training may improve balance among older adults. AIMS:This study investigated the effects of Thai traditional dance on balance performance among older women. METHODS:Forty-three women aged 60-80 years, with mean scores between 45 and 52 points on the Berg Balance Scal...

journal_title：Aging clinical and experimental research

authors： Noopud P,Suputtitada A,Khongprasert S,Kanungsukkasem V

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Falling is a significant concern for many elderly adults but identifying individuals at risk of falling is difficult, and it is not clear how elderly adults adapt to challenging walking. AIMS:The aim of the current study was to determine the effects of walking at non-preferred speeds on the coordination bet...

journal_title：Aging clinical and experimental research

authors： Craig JJ,Bruetsch AP,Huisinga JM

更新日期：2019-07-01 00:00:00

abstract：:Risk for or established malnutrition is frequent in older adults, accompanied by functional limitations, increased morbidity and mortality. Protein-energy malnutrition is often observed and leads besides other predisposing factors to sarcopenia, the increased loss of muscle mass with aging. Sarcopenia is an integral c...

journal_title：Aging clinical and experimental research

authors： Sieber CC

更新日期：2019-06-01 00:00:00

abstract：:Uncountable health care organizations, clinicians, and individuals are striving to prevent obesity and the many chronic medical conditions linked to it by advocating a healthy lifestyle that includes measures such as reducing dietary calorie intake (i.e., calorie restriction = CR and intermittent fasting = IF) or limi...

journal_title：Aging clinical and experimental research

authors： Veronese N,Reginster JY

更新日期：2019-06-01 00:00:00

abstract：:Milk is a major source of high bioavailable calcium in most developed countries with an average calcium content of 1150 mg/L, providing a ready means of meeting the daily requirements. Its content in other minerals, phosphorus, vitamins, iodine, proteins, potassium and various nutrients is supposed to be beneficial fo...

journal_title：Aging clinical and experimental research

authors： Fardellone P

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Osteoarthritis (OA) is a degenerative joint disease and a leading cause of adult disability. There is no cure for OA and there is no effective treatment to stop its progression. Current pharmacologic treatments such as analgesics and non-steroidal anti-inflammatory drugs may improve the pain and offer some r...

journal_title：Aging clinical and experimental research

authors： Messina OD,Vidal Wilman M,Vidal Neira LF

更新日期：2019-06-01 00:00:00

abstract：:Most visual and cognitive functions are affected by aging over the lifespan. In this study, our aim was to investigate the loss in sensitivity to different classes of second-order stimuli-a class of stimuli supposed to be mainly processed in extrastriate cortex-in the aging population. These stimuli will then allow on...

journal_title：Aging clinical and experimental research

authors： Reynaud A,Tang Y,Zhou Y,Hess RF

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:While most fractures are caused by falls, not all falls result in fractures. Risk factors for falls are well established, but only weak associations have been demonstrated for risk factors for fractures. Conflicting results on the implication of bone mineral density (BMD) suggest that other risk factors shou...

journal_title：Aging clinical and experimental research

authors： Langeard A,Pothier K,Chastan N,Marcelli C,Chavoix C,Bessot N

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Slow walking speed as one indicator of physical frailty has been found to be associated with deterioration of the health status. Although many reports have shown that exercise training improves motor function, it is unclear whether a group-based and short-term health promotion intervention will improve motor...

journal_title：Aging clinical and experimental research

authors： Kutsuna T,Hiyama Y,Kusaka S,Kusumoto Y,Tsuchiya J,Umeda M,Takahashi T

更新日期：2019-04-01 00:00:00

abstract：:Older adults in Latin America are at an increased risk of hospitalisation, ill health, catastrophic disability and death due to vaccine-preventable diseases such as influenza, herpes zoster, and pneumonia. The Latin American Adult Immunisation Advocacy Summit, held in Mexico City, gathered 40 experts in health, ageing...

journal_title：Aging clinical and experimental research

authors： Barratt J,Mishra V,Acton M

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Multimorbidity in older adults needs to be assessed as it is a risk factor for disability, cognitive decline, and mortality. AIMS:A community-based longitudinal study was performed to determine the incidence and to identify possible predictors of multimorbidity among multiethnic older adults population in M...

journal_title：Aging clinical and experimental research

authors： Hussin NM,Shahar S,Din NC,Singh DKA,Chin AV,Razali R,Omar MA

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Swallowing dysfunction and risk of undernutrition increase the risk of pneumonia, morbidity, and mortality. Short-term care is an unexplored care context, where many older people stay yearly. AIM:This cross-sectional study aimed to describe and analyze the relationship between swallowing dysfunction and ris...

journal_title：Aging clinical and experimental research

authors： Hägglund P,Fält A,Hägg M,Wester P,Levring Jäghagen E

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:To investigate the prevalence and related factors of cognitive impairment in community-dwelling older residents in Beijing, China. METHODS:This is a cross-sectional study. A total of 2017 older individuals aged ≥ 60 years from Beijing Longitudinal Study of Aging were included in this study. Information on d...

journal_title：Aging clinical and experimental research

authors： Han R,Tang Z,Ma L

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:In addition to the normal process of ageing, frailty, defined as a geriatric syndrome, is becoming more prevalent. Around 10% of people over 65 years and 25-50% of those aged over 85 years are frail. Frail elderly are more vulnerable to external stressors and have an increased risk of adverse health outcomes...

journal_title：Aging clinical and experimental research

authors： Windhaber T,Koula ML,Ntzani E,Velivasi A,Rizos E,Doumas MT,Pappas EE,Onder G,Vetrano DL,Roudriguez Laso A,Roudriguez Manjas L,Illario M,Roller-Wirnsberger RE,ADVANTAGE JA WP8 group.

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The palliative prognostic index (PPI) is a commonly used tool to predict the life expectancy in palliative care patients. However, there is no universal cutoff, and the accuracy of different cutoffs varies. Therefore, we conducted this meta-analysis to explore the validity and accuracy of different PPI score...

journal_title：Aging clinical and experimental research

authors： Liu Y,Su L,Wang Y,Liu S,Dong B

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Few studies have explored the activity levels of hospitalised older people and the intra-daily activity patterns in this group have not been described. AIMS:To describe the quantity and daily pattern of physical activity among hospitalised older people using two accelerometers: the ankle-worn StepWatch Acti...

journal_title：Aging clinical and experimental research

authors： Lim SER,Dodds R,Bacon D,Sayer AA,Roberts HC

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Fall-induced deaths of elderly people are a major problem. AIM AND METHODS:Using the Official Cause-of-Death Statistics of Finland, we aimed to determine the current trends in the number and age-adjusted incidence (per 100,000 persons) of fall deaths among older Finns by taking into account 50 years or olde...

journal_title：Aging clinical and experimental research

authors： Kannus P,Niemi S,Sievänen H,Parkkari J

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Statins therapy in the secondary prevention of coronary artery disease (CAD) is associated with a lower risk of adverse cardiovascular events. However, little is known regarding the association of elderly patients with nutritional risk on statin therapy. AIMS:To investigate whether older patients with CAD w...

journal_title：Aging clinical and experimental research

authors： Huang BT,Huang FY,Pu XB,Xia TL,Peng Y,Chen F,Yang Y,Liao YB,Chen M

更新日期：2018-09-01 00:00:00

abstract：:The aim of this study was to assess the effectiveness of balance training with somatosensory and neurofeedback training on dynamic and static balance in healthy, elderly adults. The sample group consisted of 45 healthy adults randomly assigned to one of the three test groups: somatosensory, neurofeedback, and a contro...

journal_title：Aging clinical and experimental research

authors： Azarpaikan A,Taheri Torbati H

更新日期：2018-07-01 00:00:00

abstract：:Parkinson's disease (PD) typically occurs in elderly people and some degree of cognitive impairment is usually present. Cognitive reserve (CR) theory was proposed to explain the discrepancy between the degree of brain pathologies and clinical manifestations. We administered a comprehensive neuropsychological battery t...

journal_title：Aging clinical and experimental research

authors： Ciccarelli N,Monaco MRL,Fusco D,Vetrano DL,Zuccalà G,Bernabei R,Brandi V,Pisciotta MS,Silveri MC

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Resistance training holds promise for nursing home residents to prevent further disabilities, falls, and fractures. Free weight as well as machine training may offer an efficient option to improve physical performance, but the feasibility of these training regimes among elderly who require continuous institu...

journal_title：Aging clinical and experimental research

authors： Johnen B,Schott N

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Heart failure (HF) patients with frailty syndrome (FS) are at higher risk of falling, decreased mobility, ability to perform the basic activities of daily living, frequent hospitalizations, and death. AIMS:The purpose of this study was to evaluate the correlations between FS and hospital readmissions, and t...

journal_title：Aging clinical and experimental research

authors： Uchmanowicz I,Kuśnierz M,Wleklik M,Jankowska-Polańska B,Jaroch J,Łoboz-Grudzień K

更新日期：2018-06-01 00:00:00